Aqueous Deficient Dry Eye
The watery part of the tear film is called aqueous. When the lacrimal gland fails to produce a sufficient amount of the aqueous layer to adequately coat the eyes surface, aqueous deficient dry eye symptoms appear.
What causes symptoms in aqueous deficient dry eye?
Consider this, tears generally have a salty taste. When the aqueous layer is deficient, the tear film become hyperosmotic. or the concentration of salt in the tears is too high. The salty tears interact with surface of the cornea causing inflammation. Basically, the extra salty tears causes burning and stinging symptoms of dry eye. Next, inflammatory mediators accumulate in tear film and begin to damage the goblet cells on the surface of the cornea. The goblet cells are important because they are responsible for the secretion of the mucin layer covering the very surface of the cornea. When the mucin layer becomes insufficient, the tear film becomes unstable and further inflammation and dry eye symptoms occur.
What can we do for inflammatory dry eye?
There are currently 2 prescription drops FDA approved for the treatment of aqueous deficient of inflammatory dry eye symptoms.
Restasis and Xiidra